General Cell Lines and Cell Cultures
Genscript Corporation CHO-K1/OPRL1/G15 Stable Cell
Following the cloning of the classical opioid receptors (mu delta and kappa) the opiate receptor like-1 (ORL1) was identified as a G-protein coupled receptor (GPCR) with 65% structure homology to the other members of the opioid family OPRL1 is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ and may be involved in the regulation of numerous brain activities particularly instinctive and emotional behaviors Recently new study results are consistent with the reported high density of ORL1 receptor mRNA in dorsal raphe nucleus and with inhibitory actions of nociceptin in cells expressing ORL1
Genscript Corporation CHO-K1/CD32B 232Thr Stable Cel
Recombinant CHO-K1 cells stably overexpress human immunoglobulin gamma Fc region receptor II-b (Fc RIIb/CD32B 232Thr) on the surface The surface expression of CD32B 232Thr is validated by FACS analysis This stable cell line product is designed for measuring binding affinity and stability of Fc region of antibodies and Fc fusion proteins or antibody based biologics binding with CD32B 232Thr GenScript also offers CD32B 232Ile stable cell line (Cat No M00587) for Fc RIIb polymorphism study
Genscript Corporation CHO-K1/mouse HVEM Stable Cell
HVEM is found on the surface of various cell types including hematopoietic and non-hematopoietic cells and is expressed mainly in spleen thymus bone marrow lung and intestines It has been identified as a canonical TNF receptor signaling through the TNF receptor-associated factors (TRAFs) leading to NF B activation Furthermore in addition to acting as a signaling receptor in binding to Ig superfamily members it acts as a ligand for these inhibitory receptors Therefore bidirectional signaling is possible for the HVEM-mediated signaling network which can be involved in positive or negative immunological reactions under different contexts
Genscript Corporation CHO-K1/human CD47 Stable Cell
Recombinant CHO-K1 cells stably overexpress human CD47 on the surface The surface expression of CD47 on this cell is validated by FACS analysis This cell line is recommended for cell-based binding assay to screening antibodies against CD47 or to measure binding affinity between CD47 and anti-CD47 antibodies
Sigma Aldrich Fine Chemicals Biosciences Histamine Quantification A
Histamine is a biogenic amine generated from the single decarboxylation of the amino acid histidine. Histamine food poisonings are allergy-like food poisonings caused by the ingestion of spoiled food containing markedly elevated histamine levelsElevated levels of bacterial fermentation can lead to elevated histamine in various food and drink sources such as fish fermented meat milk cheese beer and wine.
Genscript Corporation CHO-K1/CRF1/G15 Stable Cell L
Recombinant CHO-K1 cells stably overexpress human corticotropin releasing hormone receptor 1 (CRF1) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
American Research Products Inc Mouse Triggering receptor eXpr
Mouse Triggering receptor eXpressed on myeloid cells 2 (TREM2) ELISA kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma tissue homogenates Method Sandwich
American Research Products Inc AntiHuman CD47
Anti-Human CD47 [B6H12] In Vivo Antibody - Low Endotoxin is a in vivo antibody with human reactivity produced in mouse Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles